I got laid off last Thanksgiving....but honestly, I don't blame the economy for that. It wasn't a mass-layoff like some game developers. I mostly just blame "End of project...some gotta go". It's typical in my industry so I didn't think about it too much.
I picked up a job pretty quick (within a week, actually) and felt unbelievably fortunate for that. Now I'm working on casual Wii games and our games are selling by the truckload so overall I have nothing to worry about for the moment.
Also, last year I paid off almost all of my debts so I am positioned pretty well for the economic climate....well, once I get a little more savings that is.