Some really good mileage. I would say for anatomy studies. hold off on shades and do a series of about 10 to 20 of the same part of the anatomy, with different mediums, spending about 5 minutes or lest. as for the digital coloring, start getting use to using the F5 hot key or secondary button to constantly readjust your brush as needed. (Its an awkward route) Its will allow your work to say Digital paint rather than photo shop.